Scientific Meta-Analysis Workflow

Trigger condition

Steps

1. 1

   Search PubMed and Semantic Scholar for studies matching PICO criteria

   tool: pubmed_api · output: candidate_studies

2. 2

   Screen abstracts for inclusion: apply inclusion/exclusion criteria, output filtered list

   tool: llm · output: included_studies

3. 3

   Extract effect sizes, sample sizes, methodology, and outcome measures from each paper

   tool: llm · output: extraction_table

4. 4

   Run random-effects meta-analysis, compute pooled effect size with 95% CI

   tool: python_statsmodels · output: pooled_effect

5. 5

   Generate forest plot and Funnel plot for publication bias assessment

   tool: python_matplotlib · output: plots

6. 6

   Write PRISMA-compliant results section with heterogeneity analysis (I²)

   tool: llm · output: results_section

Expected output

Tools required